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Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials

Meinhard Kieser
Barcode 9783030495305
Paperback

Original price £108.15 - Original price £108.15
Original price
£108.15
£108.15 - £108.15
Current price £108.15

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Release Date: 20/11/2021

Edition: 2020 ed.
Genre: Science Nature & Math
Sub-Genre: Technology & Engineering
Label: Springer Nature Switzerland AG
Series: Springer Series in Pharmaceutical Statistics
Language: English
Publisher: Springer Nature Switzerland AG

This book provides an extensive overview of the principles and methods of sample size calculation and recalculation in clinical trials. Blinded sample size recalculation procedures for internal pilot study designs are considered, as well as methods for sample size reassessment in adaptive designs that use unblinded data from interim analyses.