{"product_id":"9783527351008-targeting-rna-with-small-molecules","title":"RNA as a Drug Target","description":"\u003cmeta content=\"text\/html; charset=utf-8\" http-equiv=\"Content-Type\"\u003e\u003cp\u003e\u003cspan\u003eThe Next Frontier for Medicinal Chemistry\u003cbr\u003e\u003cp\u003e\u003cb\u003eDiscover a new paradigm in drug discovery that greatly expands the space of addressable drug targets and potential novel drugs\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eExisting paradigms for drug discovery have focused largely on enzymes and other proteins as drug targets. In recent years, however, different varieties of ribonucleic acids have emerged as a viable focus for target-based drug discovery, with the potential to revolutionize the strategy and approach for this essential step in the drug development process.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eRNA as a Drug Target: The Next Frontier for Medicinal Chemistry \u003c\/i\u003eoffers a practice-oriented introduction to developing drug-like small molecules that selectively modulate both coding and non-coding RNAs. Beginning with a description and characterization of existing druggable RNAs, the book discusses how to approach different RNA targets for drug discovery. The result is a crucial resource for targeting RNAs and creating the next generation of life-saving pharmaceuticals.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eRNA as a Drug Target \u003c\/i\u003ereaders will also find:\u003c\/p\u003e \u003cul\u003e\n\u003cli\u003eA complete “toolbox” for working with RNA, from structure determination to screening and lead generation techniques\u003c\/li\u003e\n\u003cli\u003eA wide range of addressable targets and mechanisms, including splicing modulation, riboswitches, targeted degradation, and more\u003c\/li\u003e\n\u003cli\u003eAuthoritative discussion of the potential of RNA-targeted small molecule therapeutics for drugging the epitranscriptome\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003e\u003ci\u003eRNA as a Drug Target\u003c\/i\u003e provides an expert introduction to a new frontier in pharmaceutical research for medicinal chemists, biochemists, molecular biologists, and members of the pharmaceutical industry.\u003c\/p\u003e\n\u003cbr\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"Rarewaves","offers":[{"title":"Default Title","offer_id":56127981683062,"sku":"9783527351008","price":150.46,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0092\/7504\/8033\/files\/orig_38850749_1286c65d-e183-492e-825f-670d6ab7f243.jpg?v=1764391661","url":"https:\/\/www.rarewaves.com\/products\/9783527351008-targeting-rna-with-small-molecules","provider":"Rarewaves.com","version":"1.0","type":"link"}