{"product_id":"9781420084726-preclinical-drug-development","title":"Preclinical Drug Development","description":"\u003cmeta content=\"text\/html; charset=utf-8\" http-equiv=\"Content-Type\"\u003e\u003cp\u003e\u003cspan\u003ePreclinical Drug Development. \u003cp\u003e\u003cstrong\u003ePreclinical Drug Development, Second Edition\u003c\/strong\u003e discusses the broad and complicated realm of preclinical drug development. Topics range from assessment of pharmacology and toxicology to industry trends and regulatory expectations to requirements that support clinical trials. \u003c\/p\u003e\n\u003cp\u003eHighlights of the Second Edition include: \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cp\u003e \u003c\/p\u003e \u003c\/li\u003e\n\u003cli\u003ePharmacokinetics\u003c\/li\u003e\n\u003cli\u003eModeling and simulation\u003c\/li\u003e\n\u003cli\u003eFormulation and routes of administration\u003c\/li\u003e\n\u003cli\u003eToxicity evaluations\u003c\/li\u003e\n\u003cli\u003eThe assessment of drug absorption and metabolism\u003c\/li\u003e\n\u003cli\u003eInterspecies scaling \u003c\/li\u003e\n\u003cli\u003eLead molecule selection and optimization via profiling\u003c\/li\u003e\n\u003cli\u003eScreening using \u003ci\u003ein silico\u003c\/i\u003e and \u003ci\u003ein vitro\u003c\/i\u003e toxicity evaluations \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe book also includes case studies on preclinical pharmacokinetic-pharmacodynamic modeling and simulation in drug development, a review of ICH preclinical guidelines, and experimental methods used to study membrane drug transport and metabolism. This guide is a fundamental resource for medicinal chemists, biologists, and other specialists in the drug development sciences. \u003c\/p\u003e\n\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"Rarewaves","offers":[{"title":"Default Title","offer_id":41039201370209,"sku":"9781420084726","price":244.86,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0092\/7504\/8033\/products\/stand_16546134_jpg.jpg?v=1705551786","url":"https:\/\/www.rarewaves.com\/products\/9781420084726-preclinical-drug-development","provider":"Rarewaves.com","version":"1.0","type":"link"}