{"product_id":"9781118065631-high-throughput-toxicity","title":"High-Throughput Screening Methods in Toxicity Testing","description":"\u003cmeta content=\"text\/html; charset=utf-8\" http-equiv=\"Content-Type\"\u003e\u003cp\u003e\u003cspan\u003eHigh-throughput assays are part of a paradigm shift, to more cost-effective and reliable methods, in the testing of chemical and drug safety.\u003cbr\u003e\u003cp\u003e\u003cb\u003eExplores the benefits and limitations of the latest high-throughput screening methods\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eWith its expert coverage of high-throughput \u003ci\u003ein vitro\u003c\/i\u003e screening methods for toxicity testing, this book makes it possible for researchers to accelerate and streamline the evaluation and risk assessment of chemicals and drugs for toxicity. Moreover, it enables them to comply with the latest standards set forth by the U.S. National Research Council's \"Toxicity Testing in the 21st Century: A Vision and Strategy\" and the E.U.'s REACH legislation. Readers will discover a variety of state-of-the-science, high-throughput screening methods presented by a group of leading authorities in toxicology and toxicity testing.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eHigh-Throughput Screening Methods in Toxicity Testing\u003c\/i\u003e is divided into five parts:\u003c\/p\u003e \u003cul\u003e\n\u003cli\u003eGeneral aspects, including predicting the toxicity potential of chemicals and drugs via high-throughput bioactivity profiling\u003c\/li\u003e\n\u003cli\u003eAssessing different cytotoxicity endpoints\u003c\/li\u003e\n\u003cli\u003eAssessing DNA damage and carcinogenesis\u003c\/li\u003e\n\u003cli\u003eAssessing reproductive toxicity, cardiotoxicity, and haematotoxicity\u003c\/li\u003e\n\u003cli\u003eAssessing drug metabolism and receptor-related toxicity\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003eEach chapter describes method principles and includes detailed information about data generation, data analysis, and applications in risk assessment. The authors not only enumerate the advantages of each high-throughput method over comparable conventional methods, but also point out the high-throughput method's limitations and potential pitfalls. In addition, the authors describe current research efforts to make high-throughput toxicity screening even more cost effective and streamlined.\u003c\/p\u003e \u003cp\u003eThroughout the book, readers will find plenty of figures and illustrations to help them understand and perform the latest high-throughput toxicity screening methods.\u003c\/p\u003e \u003cp\u003eThis book is ideal for toxicologists and other researchers who need to implement high-throughput screening methods for toxicity testing in their laboratories as well as for researchers who need to evaluate the data generated by these methods.\u003c\/p\u003e\n\u003cbr\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"Rarewaves","offers":[{"title":"Default Title","offer_id":40898129657953,"sku":"9781118065631","price":159.24,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0092\/7504\/8033\/files\/orig_27905812.jpg?v=1722152912","url":"https:\/\/www.rarewaves.com\/products\/9781118065631-high-throughput-toxicity","provider":"Rarewaves.com","version":"1.0","type":"link"}