{"product_id":"9780849327995-antiangiogenic-cancer-therapy","title":"Antiangiogenic Cancer Therapy","description":"\u003cmeta content=\"text\/html; charset=utf-8\" http-equiv=\"Content-Type\"\u003e\u003cp\u003e\u003cspan\u003eOffers information on the process of angiogenesis and its role in tumor growth and metastasis. This title compiles the work of experts to explore angiogenesis inhibitors under clinical investigation, as well as early agents used in preclinical studies. It discusses the unique aspects of targeting and inhibiting angiogenesis. \u003cp\u003e\u003cb\u003eTop Investigators Explore the Complexities of Angiogenesis Cancer Research\u003c\/b\u003e\u003c\/p\u003e\n\u003cp\u003eThe targeting of tumor angiogenesis has evolved into one of the most widely pursued therapeutic strategies. However, as of yet, no antiangiogenic agent used as a monotherapy has demonstrated a survival benefit in a randomized Phase III trial. The combination of bevacizumab, the first FDA approved angiogenesis inhibitor, with cytotoxic regimens has led to survival benefits in cancer patients. This has raised important questions about the complexities inherent in the clinical application of angiogenesis inhibitors. \u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e\u003ci\u003eCompiles the results of four decades of progress\u003c\/i\u003e\u003c\/b\u003e \u003c\/p\u003e\n\u003cp\u003eIntegrating fundamental concepts with therapeutic strategies,\u003cb\u003e Anti-Angiogenic Cancer Therapy\u003c\/b\u003e promotes the idea that an understanding of the molecular and cellular regulation of angiogenesis leads to optimal therapeutic strategies and positive clinical results. It brings together contributions from leading researchers to provide the most authoritative and encyclopedic volume available on this subject. \u003c\/p\u003e\n\u003cli\u003eExamines the role of angiogenesis in cancer, including strategies to prolong the nonangiogenic dormant state of human tumors, molecular mechanisms and cellular regulation of angiogenesis in solid tumors and hematologic malignancies, and the regulation of angiogenesis by the tumor microenvironment.\u003c\/li\u003e\n\u003cli\u003eCovers specific molecular targets for inhibiting angiogenesis in cancer therapy. \u003c\/li\u003e\n\u003cli\u003eDiscusses clinical trial design and translational research approaches essential for identifying and developing effective angiogenesis inhibitors. \u003c\/li\u003e\n\u003cli\u003eOutlines current understanding of the molecular biology of each cancer type followed by discussions that examine strategies for targeting angiogenesis in specific cancers.\u003c\/li\u003e\n\u003cp\u003eThis volume celebrates progress made in four decades, and more importantly, it provi\u003c\/p\u003e\n\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"Rarewaves","offers":[{"title":"Default Title","offer_id":40810298245217,"sku":"9780849327995","price":372.93,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0092\/7504\/8033\/files\/92b588f1f75c8840e92157a1c211c208.png?v=1682675017","url":"https:\/\/www.rarewaves.com\/products\/9780849327995-antiangiogenic-cancer-therapy","provider":"Rarewaves.com","version":"1.0","type":"link"}